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Primary cilia in hard tissue development and diseases

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 657-678 doi: 10.1007/s11684-021-0829-6

Abstract: Primary cilia are protrusions on the surfaces of cells.Furthermore, primary cilia act as sensors of external stimuli and regulate bone homeostasis.Specifically, substances are trafficked through primary cilia by intraflagellar transport, which affectsIn this review, we summarize the roles of primary cilia in long bone development and remodeling fromtwo perspectives: primary cilia signaling and sensory mechanisms.

Keywords： primary cilia     bone     mechanical sensing     hard tissue     cilium-related bone disease     tooth    

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Lack of CFAP54 causes primary ciliary dyskinesia in a mouse model and human patients

Frontiers of Medicine doi: 10.1007/s11684-023-0997-7

Abstract: Primary ciliary dyskinesia (PCD) is a highly heterogeneous recessive inherited disorder.

Keywords： primary ciliary dyskinesia     CFAP54     cilia    

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Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Frontiers of Medicine   Pages 957-971 doi: 10.1007/s11684-023-0988-8

Abstract: Primary ciliary dyskinesia (PCD) is a congenital, motile ciliopathy with pleiotropic symptoms.axonemal heavy chain 10 (DNAH10) encodes a subunit of the inner arm dynein heavy chain in motile ciliaBased on the common axoneme structure of motile cilia and sperm flagella, DNAH10 variants areImmunostaining analysis showed the absence of DNAH10 and DNALI1 in the respiratory ciliarevealed strikingly disordered axoneme 9+2 architecture and inner dynein arm defects in the respiratory cilia

Keywords： DNAH10     mice     motile cilia     mutation     primary ciliary dyskinesia    

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Evaluation of power regeneration in primary suspension for a railway vehicle

Ruichen WANG, Zhiwei WANG

Frontiers of Mechanical Engineering 2020, Volume 15, Issue 2,   Pages 265-278 doi: 10.1007/s11465-019-0571-9

Abstract: rail vehicles, this study presents the feasibility of using power regenerating dampers (PRDs) in the primaryPRDs are configured as hydraulic electromagnetic-based railway primary vertical dampers and evaluatedof the generator, and the electromagnetic configuration provides a controllable damping force to the primaryIn several case studies, generic railway vehicle primary suspension systems that are configured to includeResults indicate that PRDs can simultaneously replace conventional primary vertical dampers, regenerate

Keywords： railway vehicle     primary damper     power regeneration     ride comfort     running safety    

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Approach for natural gas to be a primary energy source in China

Weihe HUANG, Jindian CHEN, Chuan FU, Yan HUANG

Frontiers of Engineering Management 2019, Volume 6, Issue 4,   Pages 467-476 doi: 10.1007/s42524-019-0068-6

Abstract: In the long-term adjustment of energy structure, natural gas has gradually become the primary energyFor natural gas to be the primary energy, the exploitation of gas resources must be expanded, resource

Keywords： natural gas     energy revolution     primary energy     utilization areas     approaching means    

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Effect of traditional Chinese medicine combined with Western therapy on primary hepatic carcinoma: a

Li Ma, Bin Wang, Yuanxiong Long, Hanmin Li

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 191-202 doi: 10.1007/s11684-017-0512-0

Abstract:

Primary hepatic carcinoma (PHC) is a common malignant tumor in China.systematic review with meta-analysis aimed to assess the effect of TCM combined with Western therapy on primary

Keywords： traditional Chinese medicine     primary hepatic carcinoma     meta-analysis    

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Tuning the primary selective nanochannels of MOF thin-film nanocomposite nanofiltration membranes for

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 4, doi: 10.1007/s11783-021-1474-7

Abstract:

• PA layer properties tune the primary nanochannels in MIL-101(Cr) TFN

Keywords： Porous metal organic framework     Thin-film nanocomposite membrane     Primary selective nanochannels     Nanofiltration    

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Primary hypertrophic osteoarthropathy: an update

Zeng Zhang, Changqing Zhang, Zhenlin Zhang

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 60-64 doi: 10.1007/s11684-013-0246-6

Abstract: The study of a clinically indistinguishable idiopathic form (primary hypertrophic osteoarthropathy, PHO

Keywords： digital clubbing     primary hypertrophic osteoarthropathy     prostaglandin E2 (PGE2)    

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Case report of neurofibromatosis type 1 combined with primary ciliary dyskinesia

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 933-937 doi: 10.1007/s11684-021-0860-7

Abstract: with his early-onset wet cough, sinusitis, and sperm quality decline, we considered the possibility of primaryFurther electron microscopy analysis of cilia and identification of homozygous mutations in the RSPH4A

Keywords： primary ciliary dyskinesia     neurofibromatosis     bronchiectasis     transmission electron microscopy     genetic    

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Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

ZHANG Huilan, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 11-14 doi: 10.1007/s11684-008-0003-4

Abstract: aldosterone concentration to plasma renin activity ratio (PAC/PRA ratio) as the screening test of choice for primaryhypertensive patients, we studied the clinical characteristics and the diagnostic value of PAC/PRA ratio in primaryOne hundred and twenty-six suspected primary aldosteronism patients whose PAC/PRA ratio was > 25 ng/dLThe proportion of primary aldosteronism in hypertensive patients was 14% (126/902).Primary aldosteronism affects over 10% of hypertensive patients in China.
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Health: a dream from reality to the future

Chunsong Hu,Qinghua Wu

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 233-235 doi: 10.1007/s11684-016-0444-0

Abstract: developments and the source of a person’s and his/her family’s happiness, health requires not only primary

Keywords： health promotion     primary and secondary prevention     policy prevention     infectious disease     non-communicable    

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β-Cyclodextrin promoted oxidation of primary amines to nitriles in water

Dongpo SHI, Hongbing JI, Zhong LI

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 2,   Pages 196-200 doi: 10.1007/s11705-009-0051-6

Abstract: A facile, efficient and substrate-selective oxidation of the primary amines with NaClO as oxidant catalyzedhas been developed in water for the first time, and the behavior of cyclodextrin that catalyzed the primaryIt was found that the primary amines which could form host-guest complexes with cyclodextrin were oxidized

Keywords： substrate-selective     amines oxidation     β-cyclodextrin    

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System construction of a four-side primary permanent-magnet linear motor drive mechanical press

Jintao LIANG, Zhengfeng MING, Peida LI

Frontiers of Mechanical Engineering 2020, Volume 15, Issue 4,   Pages 600-609 doi: 10.1007/s11465-020-0597-z

Abstract: A primary permanent-magnet linear motor (PPMLM) has a robust secondary structure and high force density

Keywords： mechanical press     direct drive     primary permanent-magnet linear motor (PPMLM)     servo system     active disturbance    

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Meta-analysis of the diagnostic efficiency of frequency-doubling technology for primary glaucoma

LIU Ting, HE Xiangge

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 109-114 doi: 10.1007/s11684-007-0021-7

Abstract: overall diagnostic capabilities and utility of frequency-doubling technology (FDT) in patients with primaryThe included articles are of good quality and FDT can be a highly efficient diagnostic test for primary

Keywords： inclusion     sensitivity analysis     correction     specificity     appropriate    

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Primary nucleation of lithium carbonate

Yuzhu SUN, Xingfu SONG, Jin WANG, Yan LUO, Jianguo YU

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 1,   Pages 73-77 doi: 10.1007/s11705-009-0091-y

Abstract: A set of laser apparatus was used to explore the induction period and the primary nucleation of lithiumThrough the classical theory of primary nucleation, many important properties involved in primary nucleation

Keywords： lithium carbonate     primary nucleation     reactive crystallization     induction period    

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Title Author Date Type Operation

Primary cilia in hard tissue development and diseases

Journal Article

Lack of CFAP54 causes primary ciliary dyskinesia in a mouse model and human patients

Journal Article

Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Journal Article

Evaluation of power regeneration in primary suspension for a railway vehicle

Ruichen WANG, Zhiwei WANG

Journal Article

Approach for natural gas to be a primary energy source in China

Weihe HUANG, Jindian CHEN, Chuan FU, Yan HUANG

Journal Article

Effect of traditional Chinese medicine combined with Western therapy on primary hepatic carcinoma: a

Li Ma, Bin Wang, Yuanxiong Long, Hanmin Li

Journal Article

Tuning the primary selective nanochannels of MOF thin-film nanocomposite nanofiltration membranes for

Journal Article

Primary hypertrophic osteoarthropathy: an update

Zeng Zhang, Changqing Zhang, Zhenlin Zhang

Journal Article

Case report of neurofibromatosis type 1 combined with primary ciliary dyskinesia

Journal Article

Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

ZHANG Huilan, WANG Daowen

Journal Article

Health: a dream from reality to the future

Chunsong Hu,Qinghua Wu

Journal Article

β-Cyclodextrin promoted oxidation of primary amines to nitriles in water

Dongpo SHI, Hongbing JI, Zhong LI

Journal Article

System construction of a four-side primary permanent-magnet linear motor drive mechanical press

Jintao LIANG, Zhengfeng MING, Peida LI

Journal Article

Meta-analysis of the diagnostic efficiency of frequency-doubling technology for primary glaucoma

LIU Ting, HE Xiangge

Journal Article

Primary nucleation of lithium carbonate

Yuzhu SUN, Xingfu SONG, Jin WANG, Yan LUO, Jianguo YU

Journal Article